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Probiotic confusion

Last week, I answered a question from a reader who had seen a study showing that probiotic supplements reduced cold and flu symptoms in children. He reasoned that eating yogurt every day might be a good step and wondered how much he'd have to eat to get a similar "dose" of probiotics.   To answer his question, I compared the number of active cultures in a typical probiotic supplement to the number of active cultures in a typical yogurt.

But I missed an opportunity to clarify what I think is a widespread misunderstanding about probiotics. Many people think of all probiotic supplements and foods as being somewhat interchangeable. They're not.

Probiotics: an umbrella term for thousands of different bacteria

In terms of labeling foods and supplements, the FAO/WHO defines probiotics as "Live microorganisms which when administered in adequate amounts confer a health benefit on the host."  That's any health benefit.

There are hundreds of different strains of lactobacillus bacteria and they offer a variety of potential health benefits to humans. Some colonize the large intestine, others live in the lining of the stomach, still others have an affinity for the mucus membranes in the nose.  Of the many strains likely to colonize the large intestine, for example, some may improve gut immune function, others digest complex sugars, others may benefit the host by producing vitamin K.

There are also lactobacillus bacteria that don't do much of anything to improve or defend your health. These, while harmless, would technically not be classified as probiotics--although they might still be considered "live and active cultures.". 

Foods versus supplements

Most probiotic foods contain a variety of bacterial strains--your average supermarket yogurt might contain six different bacterial strains. And the lactobacillus bacteria found in yogurt are not necessarily the same as those found in other fermented foods like kefir or kim-chi.

Many of the studies you read about use "boutique" strains that are not likely to be found in any traditionally-fermented foods. In the case of the study I mentioned above, for example, they used two trademarked strains called Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07.

Is there any point to consuming probiotic foods?

I still think there are general health benefits to eating traditionally-fermented foods like yogurt, kefir, kim-chi, kombucha, sauerkraut, and miso. Eating a variety of fermented foods, which provides a wider variety of bacterial strains, might offer a wider range of benefits.

But we need to be careful about assuming that the findings on a particular strain apply to all probiotics and probiotic foods.  If you're going for a specific therapeutic benefit, such as protecting against side effects while taking antibiotics or improving flu resistance, there's no guarantee that yogurt or any other fermented food will contain the same bacteria as were used in a particular study.

Similarly, when shopping for probiotic supplements, pay attention to the individual strains in that supplement and how they compare with the strains used in various studies you might be responding to.

COMMENTS:

Posted by: Hugh Jefferson | Oct 23, 2009 2:33:53 AM

"You make really great points but your readers should keep in mind that most yogurts on the market contain no more than 2 strains. The possible benefit of such products is likely to be minimal especially since the numbers of said cultures cannot be determined. Items such as kefir may be better due to their 10+ cultures of bacteria and fungi."

You're so right Ross. To me, it seems like things like "now with probiotics" are just ways to create hype. How can you really tell how much they include.

Not even looking at the ingredients helps that much. It's hard to tell how much of each strain that they have within the product. Due to this, I've been trying a few different probiotic supplements as of recently.

I think I've found one that I like, but it took a bit to really narrow them down. Just like products, supplements need to be chosen carefully as well.

- Hugh
http://www.imithome.org/

Posted by: josephine | Oct 18, 2009 10:23:04 PM

What food or menu meal that contain of 400mcg of folic acid,320mg of magnesium,90mg of vit. C,1.5mg of vit A,200IU of vitE?
pls reply. thanks

Posted by: ava | Oct 10, 2009 1:45:25 PM

Couldn't have said it any better. I used to think exactly like that. I used to take my pick of probiotic food and think i'm getting the maximum health benefit when in fact i wasn't even close.

i've since been eating yogurt, kombucha, kimchi, miso and kefir. Slowly incorporating more and more probiotic foods into my diet.

for kefir, i like to go to www.YourKefirSource.com for info and recipes.

Posted by: Jo Ann Hattner MPH, RD | Oct 1, 2009 12:57:14 PM

Monica, I so appreciate your writing on this very important subject. As the author of GutInsight probiotics and prebiotics for digestive health and well being I want to add that the ingestion of prebiotics will enhance the growth of the beneficial bacteria in our gut. In addition to eating yogurt or drinking kefir consider adding prebiotic food sources to your daily routine. Gut Insight has a complete listing of the natural food sources.

Posted by: Anna M | Oct 1, 2009 11:12:42 AM

Great advice on comparing strains with all the new science and research emerging around probiotic bacteria! My favorite probiotic product, Flora Sinus by Nutri-Health for nasal and sinus health, bases its formula (and the strains it uses) on a Swiss study that looked at specific probiotic strains plus N-acetly-cysteine and how this combination can support healthy, clear sinuses. It's my top seasonal allergy pick, and it's fun to delve into the research as well!
- Anna M
http://blog.nutri-health.com/

Posted by: Monica Reinagel | Sep 30, 2009 3:56:42 PM

@Greg

I assume that my homemade yogurt contains the same strains as the starter I use but I'm not sure about the proportions. I can't think how to check that short of a lab analysis.

The different strains definitely affect the taste. If you have a very acute sense of taste and the two yogurts (the starter and your homemade) taste the same to you, that might be an indication that you got close to the same balance of strains.

BTW, I just started using FAGE Greek yogurt as a starter (different strains...) and definitely notice a difference in the output. You'd have to strain it to get the super thick consistency of the FAGE but even unstrained, you can taste the family resemblence.

Posted by: Monica Reinagel | Sep 30, 2009 3:52:27 PM

@Ross,

I wouldn't assume that more strains are better than fewer. A couple of really beneficial strains might be better than half a dozen slackers.

Posted by: greg | Sep 30, 2009 3:29:04 PM

Monica,

Thanks for clarifying. Here is a follow up question which is a bit outside of nutrition but since you are a yogurt maker yourself I'm going to ask...

Lactobacillus acidophilus and Bifidobacterium lactis are the probiotics found to suppress cold and flu symptoms in that particular study. It just so happens that my favorite brand of yogurt, Brown Cow, has those very strains of active cultures in it (along with the mandatory S. thermophilus and L. bulgaricus)

It also happens that that I like to make my yogurt at home using Brown Cow as a starter - its fun, easy, way less expensive than store bought, and the more I have around the more I use it.

You reasoned in your first post that as the "Live and Active Cultures" seal certifies we are getting at least 22 billion live cultures in an 8 oz ounce cup of yogurt, that made one cup your zero-order estimate of a good "dose." Unfortunately, we don't know which cultures we are getting, but hey, life has some uncertainty.

That was a long lead in to my follow up which is really about the biology of these strains: if I am using Brown Cow as my starter, will the probiotic strains L acidophilus and Bifidis be in my yogurt (in at least the same proportion as they were in the starter) or are they going to be dominated and out competed by the S. thermophilus and L. bulgaricus. In other words, can I grow my probiotics in my yogurt or do I have to add them in separately order to get them?

Greg

Posted by: Ross | Sep 30, 2009 3:29:01 PM

You make really great points but your readers should keep in mind that most yogurts on the market contain no more than 2 strains. The possible benefit of such products is likely to be minimal especially since the numbers of said cultures cannot be determined. Items such as kefir may be better due to their 10+ cultures of bacteria and fungi. It is important to check the label before buying. Expensive yogurts aren't always better as some generics or lesser known brands can contain 6+ strains for a lower cost.

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